Integrin beta 2 anticorps

N° du produit ABIN3031375

Cet anticorps Lapin Polyclonal détecte spécifiquement Integrin beta 2 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Integrin beta 2 anticorps (ABIN3031375)

Antigène: Integrin beta 2 (ITGB2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Integrin beta 2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Integrin beta 2 anticorps

Purification: Antigen affinity purified

Immunogène: This Integrin beta 2 antibody was produced from rabbits immunized with a recombinant protein from the human ITGB2.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the Integrin beta 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Integrin beta 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur Integrin beta 2

Antigène: Integrin beta 2 (ITGB2)

Autre désignation: Integrin beta 2

Sujet: The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.

UniProt: P05107

Pathways: Signalisation NF-kappaB, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation